Gastric Parietal Cell Autoantibodies

Additional Information:

EPIC Name Test: GASTRIC PARIETAL CELL ANTIBODIES

CPT Code(s):

88346

Specimen Requirements:

Type: Serum
Container/Tube: SST
Sample Volume: 1 mL
Minimum Volume: 0.1 mL (Repeat testing is not possible with this specimen volume.)
Storage: Centrifuge, separate and transfer the serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.
Stability (collection to time of analysis/testing):

  • Refrigerated: 24 hours
  • Frozen: 1 year

Use:

  • Diagnosis of Pernicious Anemia: Gastric parietal-cell autoantibodies detected in the presence of biochemically defined pernicious anemia and vitamin B12 deficiency identify an autoimmune etiology as the cause of the subject’s pernicious anemia.
  • Prediction of Pernicious Anemia: Parietal-cell autoantibodies detected in an asymptomatic individual indicates an increased risk for the subsequent development of chronic lymphocytic gastritis, achlorhydria and pernicious anemia.

Methodology:

Indirect immunofluorescence

Reported:

1 - 10 Business Days

Reference Values:

Negative (interpretive report provided)

Performed:

Biweekly